Iontophoresis is one of the few hyperhidrosis treatments you can do at home, and the machines are not cheap, so it matters which one you buy and whether it is even sold where you live. I have been through this myself: I used an Ionomat at my dermatologist’s office, and I now use a DermaDry Total at home. This guide ranks the machines I could find solid information on and shows where each one is available, country by country.
The short answer: Dermadry is my top pick for most countries because it has a verifiable FDA record and a Health Canada licence, and its store lists the most countries. Hidroxa is a close second and has the widest European coverage. Hidrex is the long-established German option but the most expensive. Prices and availability below were checked on November 11, 2026, and they change often.
How I ranked them
I have not lab-tested these machines. I use one of them (DermaDry Total) and used an Ionomat at my dermatologist, but I have not used the others. So the ranking is based on things you can check yourself:
- Regulatory evidence. Does the maker have a clearance record in the US FDA database, and a licence in Canada? I looked these up directly instead of trusting the maker’s own claims.
- Availability. In how many countries does the brand have a store or ship to?
- Price and risk. What does it cost, and is there a warranty and a money-back guarantee?
- Areas it treats. Hands, feet and underarms, or only some.
A note on “FDA-cleared.” These machines are cleared through the FDA’s 510(k) route, which means the FDA found them substantially equivalent to a device already on the market. That is not the same as “FDA-approved,” a stricter process. All the records below are filed as iontophoresis devices. I confirmed the hyperhidrosis wording only for Dermadry, so open each record and read the intended use if it matters to you.
Disclosure: I use a Dermadry device. The Dermadry link in this post applies a reader discount code (SWEATYSWAGGY15) and is not an affiliate link. The other links are plain links to each maker’s site. The ranking uses the criteria above, and I explain every step. Treatment advice here is general information, not medical advice. The International Hyperhidrosis Society (IHhS) says to check with your own doctor before you start.
Iontophoresis machines ranked
| # | Machine | Treats | FDA record I could find | Price I saw | Best for |
|---|---|---|---|---|---|
| 1 | Dermadry | Hands, feet, underarms | Yes, K192749 (2020) | $450–$500 | Most countries, US and Canada |
| 2 | Hidroxa | Hands, feet, underarms | Yes, K241267 (2024) | $489–$535 ex VAT | Europe (widest coverage) |
| 3 | Hidrex | Hands, feet, underarms | Yes, K133033 (2015) | $695–$915 (US) | Germany and the US |
| 4 | RA Fischer “The Fischer” | Hands, feet, underarms | Older records (1990, 1997) | “Under $900” | US, insurance route |
| 5 | Saalio | Hands, feet, underarms | Yes, K191436 (2019) | €639–€649 | DE, FR, ES, IT shops |
| 6 | IontoDri | Hands, feet | None found | $269 | Tight budget, with caution |
Prices are what each maker’s own site showed on November 11, 2026 and do not include shipping or tax unless stated. “FDA record” means I found an entry in the FDA’s public 510(k) database under that maker or product name.
1. Dermadry (my top pick)
Why it ranks first: I could verify two official records myself. The FDA database lists Dermadry K192749, cleared in February 2020. Health Canada’s medical device licence database lists a DERMADRY licence (number 101550, class II, first issued in August 2018, active). Dermadry also states it is CE marked and licensed by Australia’s Therapeutic Goods Administration, but I could not check those two independently.
Availability: its store has a country selector with local currency. I found the US, Canada, the UK, Ireland, Germany, France, the Netherlands, Australia, New Zealand, the Philippines, the UAE and South Africa among the listed countries. Spain, Italy, Portugal, the Nordic countries, Poland and India were not in the selector when I checked, even though the site advertises worldwide shipping. If you live in one of those countries, confirm at checkout before you count on it.
Price: $500 for Dermadry Total (hands, feet and underarms), $475 for Hands & Feet, and $450 for Underarms. Dermadry runs frequent sales, so check the current price. See Dermadry (discount code applied).
My experience: this is the machine I own. I wrote about what it was like in the pros and cons of iontophoresis and what a real session is like.
2. Hidroxa (widest European coverage)
Why it ranks second: a Swedish company with a recent FDA record: Hidroxa SE30, K241267, cleared in October 2024. It comes with a 2-year warranty, a 50-day money-back guarantee and free shipping, according to its store.
Availability: it has separate stores for Sweden, Norway, Denmark, Finland, Germany, France, the Netherlands, Poland, Spain, Italy, the UK and the US, plus an international store. That is the widest European coverage I found.
Price: $489 for Hands & Feet or for Armpits, and $535 for the Complete machine, shown ex VAT on its US-dollar store.
Why not first: I could not find a Hidroxa entry in the Health Canada licence database, and the FDA record is newer, with less track record. Visit hidroxa.com.
3. Hidrex (long track record, highest price)
Why it ranks third: a German manufacturer making these machines since 1987 by its own account. The FDA database has Hidrex PSP1000, K133033 (2015). The current models sold in the US, such as the DVP1000 and DP450, did not appear under their own names in the FDA database. Hidrex USA states that every device it sells is FDA-cleared, which I could not independently confirm for those models. The German site says the devices carry the CE mark and the company is certified to EN ISO 13485.
Availability: hidrex.com for Germany and Hidrex USA for the United States. Two UK retailers have sold Hidrex machines, but the product pages I found were no longer live on November 11, so I did not count the UK. I found no local stores elsewhere, and the German site has a worldwide contact page if you live elsewhere.
Price: Hidrex USA lists the DVP1000 Ultimate (hands, feet and underarms) at $915 on sale, the DVP1000 Hands & Feet at $875, and the DP450 Underarms at $695, with a 60-day money-back guarantee and financing.
4. RA Fischer, “The Fischer” (US, insurance route)
Why it ranks fourth: RA Fischer is a California company founded in 1948. The FDA database has two older iontophoresis records, the MD-2 (1990) and the MD-1A (1997), but I could not match them to the current “The Fischer” model, so I can only say the company has a clearance history, not that today’s model is covered. It says it is FDA-cleared for hands, feet and underarms.
Availability: I could only confirm sales in the United States. Its main draw is that it says most major US insurance plans cover it and that its team handles prior authorization, so some patients pay little out of pocket. That is the company’s claim, so check with your insurer. Without insurance it says “under $900.” See rafischer.com.
5. Saalio (German-language shops)
Why it ranks fifth: a German-made device from Saalmann Medical with an FDA record: Saalio K191436 (2019).
Availability: sold through the retailer schwitzen.com, which has German, French, Spanish and Italian versions. Prices there were €649 for the Hands & Feet set and €639 for the underarm set. I did not find a store for the US, Canada or the UK.
6. IontoDri (cheapest, with caution)
Why it ranks last: at $269 with free shipping it is the cheapest machine on this list, and its shipping page says it ships worldwide in about 4 to 10 business days. But I found no FDA record under its name, and its site makes no regulatory claims. That does not prove it is uncleared, only that I could not verify it. IHhS advises checking that a device is cleared in your country before you buy. If you are considering a very cheap machine, ask your doctor first. Visit iontodri.com.
A machine I would not buy: Ionomat
I used an Ionomat at my dermatologist, and it appears in my older posts. The Ionomat site now says the machine is no longer made and can only be found used. If you see one for sale, you are buying a used device with no warranty. The Ionomat site now points visitors to the Saalio (number 5 above). I also cannot verify the regulatory status of unbranded devices sold on marketplaces, so I left them out of the ranking.
Where each machine is available, country by country
This is the part most guides skip. A ✓ means I found a store or a clear listing for that country on the brand’s own site. “Intl store” means Hidroxa has an international store but no country-specific one, so shipping to that country is not confirmed. “Ships” is IontoDri’s own claim that it ships worldwide. A dash means I did not find a listing, not that it is impossible to buy.
| Country | Dermadry | Hidroxa | Hidrex | Saalio | RA Fischer | IontoDri |
|---|---|---|---|---|---|---|
| United States | ✓ | ✓ | ✓ | ✓ | ✓ | Ships |
| Canada | ✓ | — | — | — | — | Ships |
| United Kingdom | ✓ | ✓ | — | — | — | Ships |
| Ireland | ✓ | Intl store | — | — | — | Ships |
| Germany | ✓ | ✓ | ✓ | ✓ | — | Ships |
| France | ✓ | ✓ | — | ✓ | — | Ships |
| Netherlands | ✓ | ✓ | — | — | — | Ships |
| Spain | — | ✓ | — | ✓ | — | Ships |
| Italy | — | ✓ | — | ✓ | — | Ships |
| Sweden, Norway, Denmark, Finland | — | ✓ | — | — | — | Ships |
| Poland | — | ✓ | — | — | — | Ships |
| Australia and New Zealand | ✓ | Intl store | — | — | — | Ships |
| Philippines | ✓ | Intl store | — | — | — | Ships |
| UAE | ✓ | Intl store | — | — | — | Ships |
| South Africa | ✓ | Intl store | — | — | — | Ships |
| India | — | Intl store | — | — | — | Ships |
On a phone, swipe the table sideways to see every brand. Checked on brand websites on November 11, 2026. Availability changes, so confirm at checkout. A country being listed does not mean the device is approved there: check your local regulator.
How to check a machine is approved where you live
- United States: search the FDA 510(k) database by the maker or product name. A prescription is often required in the US, according to the IHhS.
- Canada: search the Health Canada medical device licence database. The IHhS recommends checking for a licence before buying.
- Australia: search the TGA ARTG register.
- UK and EU: look for a CE or UKCA mark and the manufacturer’s declaration. These are the maker’s own statements, so ask the seller for the documentation.
- Elsewhere: check with your own country’s regulator. If you import a machine, also make sure it matches your local power outlet and voltage.
Safety and what to expect
The IHhS says not to use iontophoresis if you are pregnant, have a pacemaker, have a substantial metal implant in the current path (such as a joint replacement), or have a cardiac condition or epilepsy. Talk to your healthcare provider if you are not sure. Results usually need regular maintenance, typically about once a week once the sweating is under control, according to the IHhS.
For the day-to-day reality, read what a session is really like. The honest summary from my own experience: it works, but it takes time, it can sting, and the sweating comes back if you stop. If a machine is out of your budget or not sold where you live, my guide to treatments and products by country and list of products available worldwide cover other options.
Quick answers
Which iontophoresis machine is the best?
By the criteria above, Dermadry for most countries and Hidroxa for Europe. The best one for you is the one that is cleared and sold in your country and fits your budget.
Do I need a prescription?
In the US it is often required, according to the IHhS. Some sellers help you get one. Rules differ by country, so check locally.
Does iontophoresis cure hyperhidrosis?
No. It reduces sweating while you keep up the sessions, and the sweating usually returns if you stop. See my comparison of Brella, Botox, Sofdra and iontophoresis.
Can I use one for feet and underarms too?
Most of the machines above treat hands, feet and underarms, some with extra accessories. IontoDri lists hands and feet.
Machines, prices and availability change often. I update this guide when I notice changes, but always check the seller’s site before you buy.
